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The cover: The background image is a biofilm of sulfate-reducing, anaerobic bacteria Desulfovibrio desulfuricans growing on a hematite surface. Courtesy of Pacific Northwest National Laboratory. From left to right molecular-based techniques to study soil microbiology: (a) Thermal ionization mass spectrometry provides trace isotopic signature analysis. Courtesy of Pacific Northwest National Laboratory. (b) Fluorescence microscopy, digital imaging, and automated imaging analysis for the exploration of soil microbial communities structure. Image courtesy of Dr. Shane Rogers of the U.S. Environmental Protection Agency, National Risk Management Research Laboratory, who is also pictured in the image. (c) Electropherogram of bacteria-spiked water sample, where the peaks represent 16S and 23S bacterial ribosomal RNA. Courtesy of Pacific Northwest National Laboratory. (D) Fluorescence in situ hybridization (FISH) and microautoradiography to identify uptake of polycyclic aromatic hydrocarbon compounds by soil microorganisms.Courtesy of the U.S. Environmental Protection Agency, National Risk Management Research Laboratory. (E) Ethidium-bromide stained DNA isolated from oral bacteria fed ¹³C-labelled glucose. Courtesy of Pacific Northwest National Laboratory. See the “Molecular-Based Approaches to Soil Micorbiology” Symposium. p. 561–631.